A selection of the contributions presented to the conference Lost and Transformed Cities: a digital perspective, which took place in Lisbon from the 17th to the 18th of November 2016. This selection allows a threefold outlook on the city and a methodological challenge, i.e. the study of the historic city as the subject of analysis of multiple digital perspectives; the viewing and exploring of the city and its memory as a virtual museum and the impact of the digital on the creation of a contemporary urban identity. These perspectives encompass big cities and small towns; they spread from the South Mediterranean to Central Europe and from Europe to other parts of the world. This book aims for diversity in the proposed fields of research, methodologies, case studies and geography, seeking those lost and transformed cities through a digital perspective..